Polímeros: Ciência e Tecnologia
https://revistapolimeros.org.br/article/doi/10.1590/0104-1428.210062
Polímeros: Ciência e Tecnologia
Original Article

Incorporation of Aloe vera extract in bacterial nanocellulose membranes

Lya Piaia; Camila Quinetti Paes Pittella; Samara Silva de Souza; Fernanda Vieira Berti; Luismar Marques Porto

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Abstract

Nanocellulose (BNC) is a natural polymer produced by bacteria. Its structure has only glucose monomer, it has various properties such as high water holding capacity, unique nanostructure, high crystallinity and high mechanical strength. Pure BNC or in combination with different components can be used for a wide range of applications. Aloe vera is a medicinal plant with polysaccharides in its composition that has a potential for tissue regeneration and repair. The aim of this study was to evaluate the effect of incorporating Aloe vera (A. vera) into BNC membranes produced with three fractions of A. vera extract (BNC-Aloe) on the behavior of epithelial cells. Human fibroblasts and keratinocytes were shown to have increased metabolic activity and proliferation when cultured on BNC-Aloe membranes compared to control. Quantification of collagen biosynthesis was significantly higher in BNC-Aloe membranes. In conclusion, BNC-Aloe membranes are suggested as a material for the purpose of skin tissue repair.

Keywords

tissue engineering, nanocellulose, Aloe vera, fibroblasts, keratinocytes

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