Polímeros: Ciência e Tecnologia
https://revistapolimeros.org.br/article/doi/10.1590/0104-1428.20250039
Polímeros: Ciência e Tecnologia
Review Article

Advances and challenges in nanofiber production: techniques and applications in nanotechnology

Roberto da Silva Gusmão; Erandi Mendes Maciel; Walquíria Cubíssimo Frattini; Eliton Souto de Medeiros; Francisco Antonio Helfenstein Fonseca; Henrique Tria Bianco

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Abstract

This article presents a concise review of nanofiber production techniques, materials obtained by innovative technologies to produce nanofibers. The use of nanofibers has evolved significantly due to their unique properties, allowing maximization at the nanometric scale. The large-scale production capacity, simplicity in manufacturing and versatility have increased interest in several areas, especially in pharmaceuticals, for controlled drug release. Different nanofiber manufacturing techniques were explored and how each one can improve medical-pharmaceutical devices, biomaterials, nanotechnology, textile industries, air and water filters, human tissue engineering, among others. It was observed that interest in nanofibers has grown worldwide in research. Despite the advances, challenges remain to optimize production and expand knowledge in the pharmaceutical sector. Future research should focus on more economical and sustainable manufacturing processes, in addition to exploring biodegradable and biocompatible polymers to solve problems in pharmaceutical formulations.

 

 

Keywords

nanofibers, electrospinning, centrifugal spinning, melt blowing spinning, pharmaceutical applications

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