Polímeros: Ciência e Tecnologia
https://revistapolimeros.org.br/article/doi/10.1590/0104-1428.20250001
Polímeros: Ciência e Tecnologia
Original Article

Green synthesis of N-doped carbon dots from cocoa fruit skin as antibacterial

Marpongahtun; Amru Daulay; Putri; Aniza Salviana Prayugo; Roon Goei; Salmiati

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Abstract

Organic pollutants can be broken down by photocatalysis with the help of carbon dots. Also, it is widely used as a material to stop microorganisms from growing. This study synthesized N-doped carbon dots from cocoa fruit skin as a potential antibacterial. TEM images on N-CDs show the material is dispersed well without forming aggregation. The spacing of the lattice fringe formed is around 0.23 nm, corresponding to graphite's diffraction. FTIR spectra show adsorption peak difference between CDs and N-CDs is 1118 cm-1, indicating C-N stretching. UV-Vis absorption spectrum shows the formation of a peak at 294 nm, which shows the π-π* transition of sp2, PL QY of N–CDs in a water solution was about 18.25%. It has been seen that N-CDs work very quickly and kill many bacteria compared to CDs. In both CDs, the highest value for the zone of inhibition is 100 µg mL-1.

 

 

Keywords

antibacterial, cocoa fruit skin, nitrogen-doped carbon dots, Theobroma cacao L

References

1 Rachmawaty, Mu’nisa, A., Hasri, Pagarra, H., Hartati, & Maulana, Z. (2018). Active compounds extraction of cocoa pod husk (Theobroma cacao L.) and potential as fungicides. Journal of Physics: Conference Series, 1028, 012013. http://doi.org/10.1088/1742-6596/1028/1/012013.

2 Mael, S. H. (2024). Cocoa pod husk meal as a feed ingredient for livestock. Food and Energy Security, 13(5), e70003. http://doi.org/10.1002/fes3.70003.

3 Yuli, Y., & Eka, S., Rakiman, & Yazmendra, R. (2021). Biomass waste of cocoa skin for basic activated carbon as source of eco-friendly energy storage. Journal of Physics: Conference Series, 1788, 012020. http://doi.org/10.1088/1742-6596/1788/1/012020.

4 Liu, J., Li, R., & Yang, B. (2020). Carbon dots: a new type of carbon-based nanomaterial with wide applications. ACS Central Science, 6(12), 2179-2195. http://doi.org/10.1021/acscentsci.0c01306. PMid:33376780.

5 Zhao, F., Liu, Z., Sui, S., Huang, K., Yang, Y., Chen, Z., & Yin, H. (2023). Surficial amino groups coupling induced concentration-dependent fluorescence and fluorescence quantum yield of nitrogen-doped carbon quantum dots via efficient charge transfer. Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy, 294, 122542. http://doi.org/10.1016/j.saa.2023.122542. PMid:36848858.

6 Desai, M. L., Jha, S., Basu, H., Singhal, R. K., Park, T.-J., & Kailasa, S. K. (2019). Acid oxidation of muskmelon fruit for the fabrication of carbon dots with specific emission colors for recognition of Hg2+ ions and cell imaging. ACS Omega, 4(21), 19332-19340. http://doi.org/10.1021/acsomega.9b02730. PMid:31763557.

7 Chen, Z.-W., Hsieh, T.-H., & Liu, C.-P. (2022). Production of carbon dots by pulsed laser ablation: precursors and photo‐oxidase properties. Journal of the Chinese Chemical Society, 69(1), 193-199. http://doi.org/10.1002/jccs.202100271.

8 Pramudita, R., Marpongahtun, Gea, S., Daulay, A., Harahap, M., Tan, Y. Z., Goei, R., & Tok, A. I. Y. (2022). Synthesis of fluorescent citric acid carbon dots composites derived from empty fruit bunches of palm oil tree and its anti-bacterial property. Case Studies in Chemical and Environmental Engineering, 6, 100277. http://doi.org/10.1016/j.cscee.2022.100277.

9 Marpongahtun, S., Siregar, I. P. H., Irham, W. H., & Saragih, S. W. (2023). Improving carbon dots optical properties of molasses using EDTA as a passivation agent with the microwave method. Rasayan Journal of Chemistry, 16(2), 826-832. http://doi.org/10.31788/RJC.2023.1628237.

10 Wang, C.-I., Wu, W.-C., Periasamy, A. P., & Chang, H.-T. (2014). Electrochemical synthesis of photoluminescent carbon nanodots from glycine for highly sensitive detection of hemoglobin. Green Chemistry, 16(5), 2509-2514. http://doi.org/10.1039/c3gc42325e.

11 Otten, M., Hildebrandt, M., Kühnemuth, R., & Karg, M. (2022). Pyrolysis and solvothermal synthesis for carbon dots: role of purification and molecular fluorophores. Langmuir, 38(19), 6148-6157. http://doi.org/10.1021/acs.langmuir.2c00508. PMid:35502848.

12 Kurian, M., & Paul, A. (2021). Recent trends in the use of green sources for carbon dot synthesis: a short review. Carbon Trends, 3, 100032. http://doi.org/10.1016/j.cartre.2021.100032.

13 Jing, H. H., Bardakci, F., Akgöl, S., Kusat, K., Adnan, M., Alam, M. J., Gupta, R., Sahreen, S., Chen, Y., Gopinath, S. C. B., & Sasidharan, S. (2023). Green carbon dots: Synthesis, characterization, properties and biomedical applications. Journal of Functional Biomaterials, 14(1), 27. http://doi.org/10.3390/jfb14010027. PMid:36662074.

14 Wang, Y., Wu, R., Zhang, Y., Cheng, S., & Zhang, Y. (2023). High quantum yield nitrogen doped carbon dots for Ag+ sensing and bioimaging. Journal of Molecular Structure, 1283, 135212. http://doi.org/10.1016/j.molstruc.2023.135212.

15 Tariq, M., Singh, A., Varshney, N., Samanta, S. K., & Sk, M. P. (2022). Biomass-derived carbon dots as an emergent antibacterial agent. Materials Today. Communications, 33, 104347. http://doi.org/10.1016/j.mtcomm.2022.104347.

16 Sato, K., Katakami, R., Iso, Y., & Isobe, T. (2022). Surface-modified carbon dots with improved photoluminescence quantum yield for color conversion in white-light-emitting diodes. ACS Applied Nano Materials, 5(6), 7664-7669. http://doi.org/10.1021/acsanm.2c01868.

17 Meng, J., Li, S., Ding, L., Zhou, C., Jiang, R., Zhang, Q., Cheng, Z., Gauthier, M., Hu, Y., & Wu, L. (2022). Preparation of nitrogen-doped carbon dots from coke powder as a fluorescent chemosensor for selective and sensitive detection of Cr (VI). Journal of Wuhan University of Technology, Materials Science Edition, 37(6), 1096-1104. http://doi.org/10.1007/s11595-022-2639-3.

18 Saravanan, A., Maruthapandi, M., Das, P., Luong, J. H. T., & Gedanken, A. (2021). Green synthesis of multifunctional carbon dots with antibacterial activities. Nanomaterials, 11(2), 369. http://doi.org/10.3390/nano11020369. PMid:33540607.

19 Prayugo, A. S., Marpongahtun, Gea, S., Daulay, A., Harahap, M., Siow, J., Goei, R., & Tok, A. I. Y. (2023). Highly fluorescent nitrogen-doped carbon dots derived from jengkol peels (Archidendron pauciflorum) by solvothermal synthesis for sensitive Hg2+ ions detection. Biosensors and Bioelectronics: X, 14, 100363. http://doi.org/10.1016/j.biosx.2023.100363.

20 Adu, J. K., Amengor, C. D. K., Kabiri, N., Orman, E., Patamia, S. A. G., & Okrah, B. K. (2019). Validation of a simple and robust Liebermann-Burchard colorimetric method for the assay of cholesterol in selected milk products in Ghana. International Journal of Food Sciences, 2019(1), 9045938. http://doi.org/10.1155/2019/9045938. PMid:31737650.

21 Feng, S.-H., & Li, G.-H. (2017). Hydrothermal and solvothermal syntheses. In R. Xu, & Y. Xu (Eds.), Modern inorganic synthetic chemistry (pp. 73-104). Amsterdam: Elsevier. http://doi.org/10.1016/B978-0-444-63591-4.00004-5.

22 Monday, Y. N., Abdullah, J., Yusof, N. A., Rashid, S. A., & Shueb, R. H. (2021). Facile hydrothermal and solvothermal synthesis and characterization of nitrogen-doped carbon dots from palm kernel shell precursor. Applied Sciences, 11(4), 1630. http://doi.org/10.3390/app11041630.

23 Guo, J., Qin, L., & Wang, D. (2023). Carbon dots preserve strong blue emission in both aqueous and solid states and their application in intracellular temperature sensing and white light-emitting diodes. Journal of Luminescence, 257, 119690. http://doi.org/10.1016/j.jlumin.2023.119690.

24 Li, C., Liang, H., Bai, S., Zhu, J., Chen, Z., Yang, G., & Zhu, Y. (2023). Efficient color-tunable room temperature phosphorescence through carbon dot confinement in urea crystals. Journal of Luminescence, 254, 119497. http://doi.org/10.1016/j.jlumin.2022.119497.

25 Nguyen, K. G., Baragau, I.-A., Gromicova, R., Nicolaev, A., Thomson, S. A. J., Rennie, A., Power, N. P., Sajjad, M. T., & Kellici, S. (2022). Investigating the effect of N-doping on carbon quantum dots structure, optical properties and metal ion screening. Scientific Reports, 12(1), 13806. http://doi.org/10.1038/s41598-022-16893-x. PMid:35970901.

26 Bai, J., Xiao, N., Wang, Y., Li, H., Liu, C., Xiao, J., Wei, Y., Guo, Z., & Qiu, J. (2021). Coal tar pitch derived nitrogen-doped carbon dots with adjustable particle size for photocatalytic hydrogen generation. Carbon, 174, 750-756. http://doi.org/10.1016/j.carbon.2020.10.088.

27 Das, D., & Dutta, R. K. (2021). N-doped carbon dots synthesized from ethylene glycol and β-alanine for detection of Cr(VI) and 4-nitrophenol via photoluminescence quenching. ACS Applied Nano Materials, 4(4), 3444-3454. http://doi.org/10.1021/acsanm.0c03329.

28 Cai, D., Zhong, X., Xu, L., Xiong, Y., Deng, W., Zou, G., Hou, H., & Ji, X. (2025). Biomass-derived carbon dots: synthesis, modification and application in batteries. Chemical Science, 16(12), 4937-4970. http://doi.org/10.1039/D4SC08659G. PMid:40046072.

29 Liu, X., Liu, J., Zheng, B., Yan, L., Dai, J., Zhuang, Z., Du, J., Guo, Y., & Xiao, D. (2017). N-doped carbon dots: green and efficient synthesis on a large scale and their application in fluorescent pH sensing. New Journal of Chemistry, 41(19), 10607-10612. http://doi.org/10.1039/C7NJ01889D.

30 Jenab, A., Roghanian, R., Ghorbani, N., Ghaedi, K., & Emtiazi, G. (2020). The efficacy of electrospun PAN/kefiran nanofiber and kefir in mammalian cell culture: promotion of PC12 cell growth, anti-MCF7 breast cancer cells activities, and cytokine production of PBMC. International Journal of Nanomedicine, 15, 717-728. http://doi.org/10.2147/IJN.S232264. PMid:32099360.

31 Mansuriya, B. D., & Altintas, Z. (2021). Carbon dots: classification, properties, synthesis, characterization, and applications in health care: an updated review (2018-2021). Nanomaterials, 11(10), 2525. http://doi.org/10.3390/nano11102525. PMid:34684966.

32 Issa, M. A., Abidin, Z. Z., Sobri, S., Rashid, S., Mahdi, M. A., Ibrahim, N. A., & Pudza, M. Y. (2019). Facile synthesis of nitrogen-doped carbon dots from lignocellulosic waste. Nanomaterials, 9(10), 1500. http://doi.org/10.3390/nano9101500. PMid:31652527.

33 Li, Y., Liu, C., Chen, M., Zheng, Y., Tian, H., Shi, R., He, X., & Lin, X. (2022). Preparing colour-tunable tannic acid-based carbon dots by changing the pH value of the reaction system. Nanomaterials, 12(17), 3062. http://doi.org/10.3390/nano12173062. PMid:36080100.

34 Li, X. (2021). sp2 carbon-conjugated covalent organic frameworks: Synthesis, properties, and applications. Materials Chemistry Frontiers, 5(7), 2931-2949. http://doi.org/10.1039/D1QM00015B.

35 Simões, E. F. C., Leitão, J. M. M., & Silva, J. C. G. E. (2016). Carbon dots prepared from citric acid and urea as fluorescent probes for hypochlorite and peroxynitrite. Mikrochimica Acta, 183(5), 1769-1777. http://doi.org/10.1007/s00604-016-1807-6.

36 Wang, K., Geng, C., Wang, F., Zhao, Y., & Ru, Z. (2021). Urea-doped carbon dots as fluorescent switches for the selective detection of iodide ions and their mechanistic study. RSC Advances, 11(44), 27645-27652. http://doi.org/10.1039/D1RA04558J. PMid:35480658.

37 Olla, C., Cappai, A., Porcu, S., Stagi, L., Fantauzzi, M., Casula, M. F., Mocci, F., Corpino, R., Chiriu, D., Ricci, P. C., & Carbonaro, C. M. (2023). Exploring the impact of nitrogen doping on the optical properties of carbon dots synthesized from citric acid. Nanomaterials, 13(8), 1344. http://doi.org/10.3390/nano13081344. PMid:37110929.

38 Ray, P., Moitra, P., & Pan, D. (2022). Emerging theranostic applications of carbon dots and its variants. View, 3(2), 20200089. http://doi.org/10.1002/VIW.20200089.

39 Quan, L., Jiang, W., Li, H., Li, H., Wang, Q., & Chen, L. (2022). Intelligent intra-row robotic weeding system combining deep learning technology with a targeted weeding mode. Biosystems Engineering, 216, 13-31. http://doi.org/10.1016/j.biosystemseng.2022.01.019.

40 Rajapandi, S., Pandeeswaran, M., & Kousalya, G. N. (2022). Novel green synthesis of N-doped carbon dots from fruits of Opuntia ficus-indica as an effective catalyst for the photocatalytic degradation of methyl orange dye and antibacterial studies. Inorganic Chemistry Communications, 146, 110041. http://doi.org/10.1016/j.inoche.2022.110041.

41 Wen, F., Li, P., Meng, H., Yan, H., Huang, X., Cui, H., & Su, W. (2022). Nitrogen-doped carbon dots/curcumin nanocomposite for combined photodynamic/photothermal dual-mode antibacterial therapy. Photodiagnosis and Photodynamic Therapy, 39, 103033. http://doi.org/10.1016/j.pdpdt.2022.103033. PMid:35905831.
 

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