Surface modification of poly(ε-caprolactone) electrospun fibers with bone powder by DBD

Marcos Rodrigues Oliveira; Lauriene Gonçalves da Luz Silva; Brenda Jakellinny de Sousa Nolêto; Gabriely Gonçalves Lima; Renan Matos Monção; Marcos Cristino de Sousa Brito; Lucas Pereira da Silva; Ediones Maciel de Sousa; Thercio Henrique de Carvalho Costa; Fernanda Roberta Marciano; Rômulo Ribeiro Magalhães de Sousa

doi:10.1590/0104-1428.20240091

Original Article

Surface modification of poly(ε-caprolactone) electrospun fibers with bone powder by DBD

Marcos Rodrigues Oliveira; Lauriene Gonçalves da Luz Silva; Brenda Jakellinny de Sousa Nolêto; Gabriely Gonçalves Lima; Renan Matos Monção; Marcos Cristino de Sousa Brito; Lucas Pereira da Silva; Ediones Maciel de Sousa; Thercio Henrique de Carvalho Costa; Fernanda Roberta Marciano; Rômulo Ribeiro Magalhães de Sousa

http://dx.doi.org/10.1590/0104-1428.20240091 Polímeros: Ciência e Tecnologia, vol.35, n2, e20250019, 2025

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Abstract

Poly(ε-caprolactone) (PCL) is a biodegradable polyester with promising properties in tissue engineering, particularly in the creation of living structures for regenerative medicine. This study focused on the surface properties of electrospun PCL membranes combined with bone powder, treated using Dielectric Barrier Discharge (DBD) plasma in argon and atmospheric air environments. The electrospinning technique was employed for its ability to produce fibrous scaffolds that mimic the extracellular matrix, enhancing cell adhesion and proliferation. Scanning Electron Microscopy (SEM) results indicated that the morphology of the electrospun samples remained unchanged, exhibiting random fiber orientation and the presence of hydroxyapatite, although it was not fully incorporated. Infrared spectroscopy confirmed the characteristic polymer groups, and contact angle measurements demonstrated the hydrophobic nature of the films. However, increasing the plasma exposure did not entirely convert the surface to a hydrophilic state.

Keywords

biological, plasma, poly(ε-caprolactone), surface modification

References

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Surface modification of poly(ε-caprolactone) electrospun fibers with bone powder by DBD

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Polímeros: Ciência e Tecnologia