Polímeros: Ciência e Tecnologia
https://revistapolimeros.org.br/article/doi/10.1590/0104-1428.20220060
Polímeros: Ciência e Tecnologia
Original Article

Release of oregano essential oil from PHBV films in simulated food conditionsa

Renata Cerruti da Costa; Ana Paula Ineichen; Cristiano da Silva Teixeira; Ismael Casagrande Bellettini; Larissa Nardini Carli

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Abstract

Poly(hydroxybutyrate-co-hydroxyvalerate) – PHBV plays an important role in sustainability and food safety. In this work, active packaging with antimicrobial properties was analyzed for the controlled release of active compound in three environments (acidic aqueous foods, fresh foods, and fatty foods). The compositions were produced with the addition of sepiolite nanoparticles (Sep) and oregano essential oil (OEO). The GC-MS analysis detected the presence of 3-methyl-4-isopropyl phenol as the primary constituent of the OEO (71.7%). The characterization of the films by FTIR and SEM confirmed the presence of additives, and the quantification of OEO and thermal stability of the nanocomposites was verified by TGA. Four kinetic models were used to analyze the release profile. Our findings indicate that it is possible to adjust the kinetic release of the OEO by varying the composition of the films, which is a promising alternative for producing an antibacterial biomaterial for application in food packaging.

 

 

Keywords

biodegradable polymer, controlled release, food packaging, polymer nanocomposites, oregano essential oil

References

1 Huang, C., Liao, Y., Zou, Z., Chen, Y., Jin, M., Zhu, J., Abdalkarim, S. Y. H., Zhou, Y., & Yu, H.-Y. (2022). Novel strategy to interpret the degradation behaviors and mechanisms of bio- and non-degradable plastics. Journal of Cleaner Production, 355, 131757. http://dx.doi.org/10.1016/j.jclepro.2022.131757.

2 Costa, R. C., Daitx, T. S., Mauler, R. S., Silva, N. M., Miotto, M., Crespo, J. S., & Carli, L. N. (2020). Poly(hydroxybutyrate-co-hydroxyvalerate)-based nanocoposites for antimicrobial active food packaging containing oregano essential oil. Food Packaging and Shelf Life, 26, 100602. http://dx.doi.org/10.1016/j.fpsl.2020.100602.

3 Torres-Giner, S., Hilliou, L., Melendez-Rodriguez, B., Figueroa-Lopez, K. J., Madalena, D., Cabedo, L., Covas, J. A., Vicente, A. A., & Lagaron, J. M. (2018). Melt processability, characterization, and antibacterial activity of compression-molded green composite sheets made of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) reinforced with coconut fibers impregnated with oregano essential oil. Food Packaging and Shelf Life, 17, 39-49. http://dx.doi.org/10.1016/j.fpsl.2018.05.002.

4 Rhim, J.-W., Park, H.-M., & Ha, C.-S. (2013). Bio-nanocomposites for food packaging applications. Progress in Polymer Science, 38(10-11), 1629-1652. http://dx.doi.org/10.1016/j.progpolymsci.2013.05.008.

5 Requena, R., Jiménez, A., Vargas, M., & Chiralt, A. (2016). Poly[(3-hydroxybutyrate)-co-(3-hydroxyvalerate)] active bilayer films obtained by compression moulding and applying essential oils at the interface. Polymer International, 65(8), 883-891. http://dx.doi.org/10.1002/pi.5091.

6 Kamal, R., Razzaq, A., Shah, K. A., Khan, Z. U., Khan, N. U., Menaa, F., Iqbal, H., & Cui, J. (2022). Evaluation of cephalexin-loaded PHBV nanofibers for MRSA-infected diabetic foot ulcers treatment. Journal of Drug Delivery Science and Technology, 71, 103349. http://dx.doi.org/10.1016/j.jddst.2022.103349.

7 Chen, Y., Abdalkarim, S. Y. H., Yu, H.-Y., Li, Y., Xu, J., Marek, J., Yao, J., & Tam, K. C. (2020). Double stimuli-responsive cellulose nanocrystals reinforced electrospun PHBV composites membrane for intelligent drug release. International Journal of Biological Macromolecules, 155, 330-339. http://dx.doi.org/10.1016/j.ijbiomac.2020.03.216. PMid:32229207.

8 Li, F., Abdalkarim, S. Y. H., Yu, H.-Y., Zhu, J., Zhou, Y., & Guan, Y. (2020). Bifunctional reinforcement of green biopolymer packaging nanocomposites with natural cellulose nanocrystal–rosin hybrids. ACS Applied Bio Materials, 3(4), 1944-1954. http://dx.doi.org/10.1021/acsabm.9b01100. PMid:35025317.

9 Carli, L. N., Daitx, T. S., Guégan, R., Giovanela, M., Crespo, J. S., & Mauler, R. S. (2015). Biopolymer nanocomposites based on poly(hydroxybutyrate-co-hydroxyvalerate) reinforced by a non-ionic organoclay. Polymer International, 64(2), 235-241. http://dx.doi.org/10.1002/pi.4781.

10 Li, F., Yu, H.-Y., Li, Y., Abdalkarim, S. Y. H., Zhu, J., & Zhou, Y. (2021). “Soft-rigid” synergistic reinforcement of PHBV composites with functionalized cellulose nanocrystals and amorphous recycled polycarbonate. Composites. Part B, Engineering, 206, 108542. http://dx.doi.org/10.1016/j.compositesb.2020.108542.

11 The European Commission. (2011). Commission Regulation (EU) No 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food. Brussels: Official Journal of the European Union.

12 Zygoura, P. D., Paleologos, E. K., & Kontominas, M. G. (2011). Changes in the specific migration characteristics of packaging-food simulant combinations caused by ionizing radiation: effect of food simulant. Radiation Physics and Chemistry, 80(8), 902-910. http://dx.doi.org/10.1016/j.radphyschem.2011.03.020.

13 Requena, R., Vargas, M., & Chiralt, A. (2017). Release kinetics of carvacrol and eugenol from poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) films for food packaging applications. European Polymer Journal, 92, 185-193. http://dx.doi.org/10.1016/j.eurpolymj.2017.05.008.

14 Zhang, Y., Huo, M., Zhou, J., Zou, A., Li, W., Yao, C., & Xie, S. (2010). DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. The AAPS Journal, 12(3), 263-271. http://dx.doi.org/10.1208/s12248-010-9185-1. PMid:20373062.

15 Siswanto, A., Fudholi, A., Nugroho, A. K., & Martono, S. (2015). In vitro release modeling of aspirin floating tablets using DDSolver. Indonesian Journal of Pharmacy, 26(2), 94-102.

16 Fernández-Pan, I., Maté, J. I., Gardrat, C., & Coma, V. (2015). Effect of chitosan molecular weight on the antimicrobial activity and release rate of carvacrol-enriched films. Food Hydrocolloids, 51, 60-68. http://dx.doi.org/10.1016/j.foodhyd.2015.04.033.

17 Yu, J. T., Bouwer, E. J., & Coelhan, M. (2006). Occurrence and biodegradabilty studies of selected pharmaceuticals and personal care products in sewage effluent. Agricultural Water Management, 86(1-2), 72-80. http://dx.doi.org/10.1016/j.agwat.2006.06.015.

18 Bilotti, E., Fischer, H. R., & Peijs, T. (2008). Polymer nanocomposites based on needle-like sepiolite clays: effect of functionalizes polymers on the dispersion of nanofiller, crystallinity, and mechanical properties. Journal of Applied Polymer Science, 107(2), 1116-1123. http://dx.doi.org/10.1002/app.25395.

19 Liu, Q.-S., Zhu, M.-F., Wu, W.-H., & Qin, Z.-Y. (2009). Reducing the formation of six-membered ring ester during thermal degradation of biodegradable PHBV to enhance its thermal stability. Polymer Degradation & Stability, 94(1), 18-24. http://dx.doi.org/10.1016/j.polymdegradstab.2008.10.016.

20 Tunç, S., Duman, O., & Polat, T. G. (2016). Effects of montmorillonite on properties of methyl cellulose/carvacrol based active antimicrobial nanocomposites. Carbohydrate Polymers, 150, 259-268. http://dx.doi.org/10.1016/j.carbpol.2016.05.019. PMid:27312637.

21 Choi, J. S., & Park, W. H. (2004). Effect of biodegradable plasticizers on thermal and mechanical properties of poly(3-hydroxybutyrate). Polymer Testing, 23(4), 455-460. http://dx.doi.org/10.1016/j.polymertesting.2003.09.005.

22 Zhu, P., Chen, Y., Fang, J., Wang, Z., Xie, C., Hou, B., Chen, W., & Xu, F. (2016). Solubility and solution thermodynamics of thymol in six pure organic solvents. The Journal of Chemical Thermodynamics, 92, 198-206. http://dx.doi.org/10.1016/j.jct.2015.09.010.

23 Costa, P., & Lobo, J. M. S. (2001). Modeling and comparison of disolution profiles. European Journal of Pharmaceutical Sciences, 13(2), 123-133. http://dx.doi.org/10.1016/S0928-0987(01)00095-1. PMid:11297896.

24 Siepmann, J., & Peppas, N. A. (2001). Modeling of drug release from delivery sustems based on hydroxypropyl methylcellulose (HPMC). Advanced Drug Delivery Reviews, 48(2-3), 139-157. http://dx.doi.org/10.1016/S0169-409X(01)00112-0. PMid:11369079.

25 Mehran, M., Masoum, S., & Memarzadeh, M. (2020). Microencapsulation of Mentha spicata essential oil by spray druing: optimization, characterization, release kinetics of essential oil from microcapsules in food models. Industrial Crops and Products, 154, 112694. http://dx.doi.org/10.1016/j.indcrop.2020.112694.

26 Peppas, N. A., & Sahlin, J. J. (1989). A simple equation for the description of solute release. III. Coumpling of diffusion and relaxation. International Journal of Pharmaceutics, 57(2), 169-172. http://dx.doi.org/10.1016/0378-5173(89)90306-2.

27 Whitehead, F. A., & Kasapis, S. (2022). Modelling the mechanism and kinetics of ascorbic acid diffusion in genipin-crosslinked gelatin and chitosan networks at distinct pH. Food Bioscience, 46, 101579. http://dx.doi.org/10.1016/j.fbio.2022.101579.
 

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